Two cases of SAPHO syndrome accompanied by classic features of Behcet’s disease and review of the literature
Autor: | Hiroki Yabe, Yoji Takano, Shun-ichi Miyakawa, Michiya Kihara, Masanori Nakayama, Yukio Horiuchi, Eiki Nomura |
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Rok vydání: | 2007 |
Předmět: |
Male
SAPHO syndrome Knee arthritis medicine.medical_specialty Palmoplantar pustulosis Iritis Behcet's disease Disease Rheumatology Internal medicine Humans Medicine Aged business.industry Behcet Syndrome Acquired Hyperostosis Syndrome Anti-Inflammatory Agents Non-Steroidal Sacroiliitis Glaucoma General Medicine Hyperostosis Middle Aged medicine.disease Dermatology Surgery Treatment Outcome Female business Complication Osteosclerosis |
Zdroj: | Clinical Rheumatology. 27:133-135 |
ISSN: | 1434-9949 0770-3198 |
DOI: | 10.1007/s10067-007-0697-8 |
Popis: | We describe two patients with SAPHO (synovitis-acne-pustulosis-hyperostosis-ostitis) syndrome who presented some of the classic features of Behcet's disease. The first case is a man diagnosed as SAPHO at 74 years old. His major complaint is pain and swelling of the bilateral sterno-clavicular region for more than 14 years. Another conspicuous complication was bilateral glaucoma and episodes of iritis were recognized during the follow-up period. The second case is a 65-year-old woman, who first consulted us with right knee pain. As she had a past history of palmoplantar pustulosis and anterior chest pain, her sterile knee arthritis was diagnosed as SAPHO. She also had been suffering from recurrent oral aphthous ulceration since 6 months before visiting our hospital. Considering the clinical courses of our two cases and a review of five previously reported cases, these conditions may imply that classic features of Behcet's disease are minor complications of SAPHO syndrome. Human leukocyte antigen typing and frequent association of sacroiliitis in our cases and in the review of the literature for SAPHO syndrome with some of the classic features of Behcet's disease may indicate this condition to be a closely related disease with seronegative spondylo-arthritis. |
Databáze: | OpenAIRE |
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