| Autor: |
Howard L. McLeod, Mark J. Ratain, Michael J. Morris, M. Eileen Dolan, Susan G. Dorsey, Michiaki Kubo, Yusuke Nakamura, Michael J. Kelley, Michael A. Carducci, John F. Mahoney, Paula N. Friedman, Deanna L. Kroetz, Ivo Shterev, Phillip G. Febbo, Eric J. Small, Cynthia L. Renn, Flora Mulkey, Stefanie D. Krens, Dorothy Watson, Lois Weisman, Cameron Lassiter, Alexander B. Sibley, Heather E. Wheeler, Yoichi Furukawa, Susan Halabi, Jai Patel, William Kevin Kelly, Chen Jiang, Claudia Wing, Sherrie Lessans, Kouros Owzar, Daniel L. Hertz |
| Rok vydání: |
2023 |
| Popis: |
Sensitivity to mechanical stimuli with Von Frey filaments for C57BL/6J mice and litter-mates heterozygous for VAC14 prior to docetaxel treatment. The figure displays the estimate of the proportion of mice without a hind-paw withdrawal response to stimulation by each Von Frey fiber weight, e.g., no mice respond to fibers {less than or equal to}0.2 g and all mice respond to fibers{greater than or equal to}1.4 g. The VAC14 heterozygous mice (hatched line) are more likely than wild-type mice (solid line) to respond, meaning they are more sensitive to nociceptive stimuli (p=0.0012). Gray lines denote 95% confidence intervals. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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