Selligueain A, a novel highly sweet proanthocyanidin from the rhizomes of Selliguea feei
| ISSN: | 0163-3864 |
|---|---|
| Přístupová URL adresa: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250fb7f06e43db9b90300ae7eeb06597 https://pubmed.ncbi.nlm.nih.gov/8254348 |
| Přírůstkové číslo: | edsair.doi.dedup.....250fb7f06e43db9b90300ae7eeb06597 |
| Autor: | Soefjan Tsauri, Myung Sook Chung, Kosasih Padmawinata, Leonardus B.S. Kardono, John M. Pezzuto, Nam-In Baek, A. Douglas Kinghorn, Lisa A. Shamon, Djaja D. Soejarto |
| Rok vydání: | 1993 |
| Předmět: |
Male
Salmonella typhimurium Salmonella Taste Magnetic Resonance Spectroscopy Astringent Pharmaceutical Science medicine.disease_cause Analytical Chemistry Anthocyanins chemistry.chemical_compound Mice Selligueain A Drug Discovery Botany medicine Animals Humans Proanthocyanidins Food science Pharmacology Aqueous solution Plants Medicinal Mutagenicity Tests Organic Chemistry Sweetness Rhizome Complementary and alternative medicine chemistry Proanthocyanidin Indonesia Sweetening Agents Molecular Medicine |
| Zdroj: | Journal of natural products. 56(9) |
| ISSN: | 0163-3864 |
| Popis: | Selligueain A, a novel sweet trimeric proanthocyanidin with a doubly linked A unit, has been isolated from the rhizomes of Selliguea feei collected in Indonesia. The structure of this substance was established as epiafzelechin-(4 beta-->8, 2 beta-->O-->7)-epiafzelechin-(4 beta-->8)-afzelechin [1], on the basis of a combination of spectral and chemical methods. The compound was not acutely toxic for mice and not mutagenic in a forward mutation assay utilizing Salmonella typhimurium strain TM677. Selligueain A [1] was rated by a taste panel as exhibiting about 35 times the sweetness intensity of a 2% w/v aqueous sucrose solution, and at a concentration of 0.5% w/v in H2O was perceived as pleasant-tasting rather than astringent. |
| Databáze: | OpenAIRE |
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