Porous composite prosthetic pylon for integration with skin and bone
| Autor: | Protasov Mv, Vladimir Moxson, Oleg V. Galibin, J. Pilling, Natalia M. Yudintseva, Irina G. Belyaeva, Potokin Il, Mark Pitkin, Volodimir Duz, Pinaev Gp, Grigory Raykhtsaum, Miralda I. Blinova, Julie V. Chihovskaya |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Male
Percutaneous Materials science Dermatologic Surgical Procedures Artificial Limbs Porous composite External limb prosthesis Prosthesis Design Osseointegration Article Amputation Surgical Bone and Bones Composite structure Amputees Skin Physiological Phenomena Bone cell Pylon Animals Rats Wistar Skin Rehabilitation Models Theoretical Biomechanical Phenomena Rats Disease Models Animal Porosity Biomedical engineering |
| Popis: | This article presents results of the further development and testing of the "skin and bone integrated pylon" (SBIP-1) for percutaneous (through skin) connection of the residual bone with an external limb prosthesis. We investigated a composite structure (called the SBIP-2) made of titanium particles and fine wires using mathematical modeling and mechanical testing. Results showed that the strength of the pylon was comparable with that of anatomical bone. In vitro and in vivo animal studies on 30 rats showed that the reinforcement of the composite pylon did not compromise its previously shown capacity for inviting skin and bone cell ingrowth through the device. These findings provide evidence for the safe and reliable long-term percutaneous transfer of vital and therapeutic substances, signals, and necessary forces and moments from a prosthetic device to the body. |
| Databáze: | OpenAIRE |
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