Plasma ghrelin levels in patients with short bowel syndrome
| Autor: | Martin Haluzik, Michal Krsek, Kotrlíková E, M Rosická, Zdena Lacinova, V Justová, Z Jarkovská, Jarmila Svobodová |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Leptin Male Short Bowel Syndrome medicine.medical_specialty Peptide Hormones Receptors Cell Surface Peptide hormone Body Mass Index Endocrinology Internal medicine medicine Humans Insulin-Like Growth Factor I Aged Leptin receptor business.industry Stomach digestive oral and skin physiology General Medicine Middle Aged Short bowel syndrome medicine.disease Growth hormone secretion Ghrelin Nutrition Disorders Insulin-Like Growth Factor Binding Protein 1 medicine.anatomical_structure Insulin-Like Growth Factor Binding Protein 3 Body Composition Receptors Leptin Female business hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Endocrine research. 28(1-2) |
| ISSN: | 0743-5800 |
| Popis: | Ghrelin is a novel peptide hormone which was identified as an endogenous growth hormone secretagogue. It is mainly secreted in the stomach, but important sites of its secretion are other parts of the gastrointestinal tract. Ghrelin is thought to be involved not only in regulation of growth hormone secretion but also in regulation of food intake and nutritional status. This study was aimed to investigate the changes in plasma ghrelin levels in patients with short bowel syndrome. Twenty-four patients with malnutrition due to short bowel syndrome and eleven healthy controls were included in the study. They underwent clinical examination and assessment of plasma or serum levels of ghrelin leptin, soluble leptin receptor, IGF-I, IGFBP-1 and IGFBP-3. Plasma ghrelin levels were decreased in patients with short bowel syndrome (p |
| Databáze: | OpenAIRE |
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