A Tool for Rapid Assessment of Functional Outcomes in Patients with Head and Neck Cancer
| Autor: | Volker Hans Schartinger, Sebastian Gasser, Veronika Innerhofer, Timo Gottfried, Daniel Dejaco, Teresa Bernadette Steinbichler, Anna Lettenbichler-Haug, Robert Gassner, Roland Moschen, David Riedl, Herbert Riechelmann, Gerhard Rumpold, Felix Riechelmann, Oliver Galvan, Robert Stigler |
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| Rok vydání: | 2021 |
| Předmět: |
Cancer Research
medicine.medical_specialty business.industry Head and neck cancer Neoplasms. Tumors. Oncology. Including cancer and carcinogens health status medicine.disease Article functional outcomes Inter-rater reliability head and neck neoplasms Mood Oncology Scale (social sciences) surveys and questionnaires questionnaire design Content validity medicine Physical therapy Criterion validity In patient business RC254-282 Reliability (statistics) |
| Zdroj: | Cancers Cancers, Vol 13, Iss 5529, p 5529 (2021) Volume 13 Issue 21 |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers13215529 |
| Popis: | Head and neck cancer (HNC) and its treatment can lead to various functional impairments. We developed and validated an instrument for rapid physician-rated assessment of basic functional outcomes in HNC patients. HNC-relevant functional domains were identified through a literature review and assigned to verbal ratings based on observable criteria. The instrument draft was subjected to systematic expert review to assess its face and content validity. Finally, the empirical validity, reliability, and responsiveness of the expert-adapted Functional Integrity in Head and Neck Cancer (HNC-FIT) scales were assessed in healthy controls and in HNC patients. A matrix of the 6 functional domains of oral food intake, respiration, speech, pain, mood, and neck and shoulder mobility was created, each with 5 verbal rating levels. Face and content validity levels of the HNC-FIT scales were judged to be adequate by 17 experts. In 37 control subjects, 24 patients with HNC before treatment, and in 60 HNC patients after treatment, the HNC-FIT ratings in the 3 groups behaved as expected and functional domains correlated closely with the outcome of corresponding scales of the EORTC-HN35-QoL questionnaire, indicating good construct and criterion validity. Interrater reliability (rICC) was ≥0.9 for all functional domains and retest reliability (rICC) was ≥0.93 for all domains except mood (rICC = 0.71). The treatment effect size (eta-square) as a measure of responsiveness was ≥0.15 (p < 0.01) for fall domains except for breathing and neck and shoulder mobility. The median HNC-FIT scale completion time was 1 min 17 s. The HNC-FIT scale is a rapid tool for physician-rated assessment of functional outcomes in HNC patients with good validity, reliability, and responsiveness. |
| Databáze: | OpenAIRE |
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