Pulling out the 1%:whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries
| Autor: | Nikola Theodossiev, Cristina Valdiosera, Simon Gravel, Diana Dimitrova, Yingrui Li, Krasimir Leshtakov, M. Thomas P. Gilbert, William J. Greenleaf, Martin Sikora, Andrés Moreno-Estrada, Meredith L. Carpenter, Morten E. Allentoft, Sonia Guillén, Hannes Schroeder, Eske Willerslev, Georgi Nekhrizov, Karla Sandoval, Jason D. Buenrostro, Morten Rasmussen, Jun Wang, Davide Pettener, Carlos Bustamante, Donata Luiselli |
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| Přispěvatelé: | Carpenter ML, Buenrostro JD, Valdiosera C, Schroeder H, Allentoft ME, Sikora M, Rasmussen M, Gravel S, Guillén S, Nekhrizov G, Leshtakov K, Dimitrova D, Theodossiev N, Pettener D, Luiselli D, Sandoval K, Moreno-Estrada A, Li Y, Wang J, Gilbert MT, Willerslev E, Greenleaf WJ, Bustamante CD. |
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Male
0106 biological sciences Adolescent Genomics Computational biology Biology 010603 evolutionary biology 01 natural sciences Genome Bone and Bones Article Deep sequencing 03 medical and health sciences Principal Component Analysi Neanderthal genome MTDNA Genetics Humans ANCIENT DNA Genetics(clinical) Genomic library Environmental DNA Child History Ancient Genetics (clinical) Gene Library 030304 developmental biology Principal Component Analysis 0303 health sciences Fossils Shotgun sequencing whole genome sequence High-Throughput Nucleotide Sequencing Nucleic Acid Hybridization DNA Mummies Sequence Analysis DNA aDNA sequencing librarie Ancient DNA RNA Human genome Tooth Hair |
| Zdroj: | Carpenter, M L, Buenrostro, J D, Valdiosera Morales, C, Schroeder, H, Allentoft, M E, Sikora, M, Rasmussen, M, Gravel, S, Guillén, S, Nekhrizov, G, Leshtakov, K, Dimitrova, D, Theodossiev, N, Pettener, D, Luiselli, D, Sandoval, K, Moreno-Estrada, A, Li, Y, Wang, J, Gilbert, T, Willerslev, E, Greenleaf, W J & Bustamante, C D 2013, ' Pulling out the 1% : whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries ', American Journal of Human Genetics, vol. 93, no. 5, pp. 852-864 . https://doi.org/10.1016/j.ajhg.2013.10.002 |
| Popis: | Most ancient specimens contain very low levels of endogenous DNA, precluding the shotgun sequencing of many interesting samples because of cost. Ancient DNA (aDNA) libraries often contain |
| Databáze: | OpenAIRE |
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