Short- and long-term outcomes of endoscopic submucosal dissection for early gastric cancer in elderly patients aged 75 years and older
| Autor: | Takeyoshi Minagawa, Shunichi Okushiba, Shinya Fujie, Hideyuki Ihara, Michiaki Hirayama, Ryoji Fujii, Hitoshi Kondo, Yumiko Oyamada, Tomohiro Kimura, Naohito Yoshizaki, Tetsuya Sumiyoshi |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty Endoscopic Mucosal Resection Perforation (oil well) Malignancy 03 medical and health sciences Postoperative Complications 0302 clinical medicine Stomach Neoplasms medicine Humans Lymph node Aged Retrospective Studies Aged 80 and over business.industry Respiratory disease Gastroenterology Cancer General Medicine Endoscopic submucosal dissection medicine.disease Surgery Early Gastric Cancer Survival Rate Pneumonia Treatment Outcome medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology business Follow-Up Studies |
| Zdroj: | Gastric Cancer. 20:489-495 |
| ISSN: | 1436-3305 1436-3291 |
| DOI: | 10.1007/s10120-016-0628-y |
| Popis: | Only a few studies have reported long-term outcomes for endoscopic submucosal dissection (ESD) of early gastric cancer (EGC) in elderly patients. The aim of this study was to evaluate the efficacy of ESD for EGC in elderly patients ≥75 years with respect to both short- and long-term outcomes. We reviewed the clinical data of elderly patients ≥75 years who had undergone ESD for EGC at Tonan Hospital from January 2003 to May 2010. A total of 177 consecutive patients, including 145 with curative resection (CR) and 32 with noncurative resection (non-CR), were examined. Of the 32 patients with non-CR, 15 underwent additional surgery, and lymph node metastases were found in 3 patients. The remaining 17 patients were followed without additional surgery because of advanced age or poor general condition. Procedure-related complications, such as post-ESD bleeding, perforation and pneumonia, were within the acceptable range. The 5-year survival rates of patients with CR, those with additional surgery after non-CR, and those without additional surgery after non-CR were 84.6, 73.3, and 58.8 %, respectively. No deaths were attributable to the original gastric cancer; patients succumbed to other illnesses, including malignancy and respiratory disease. In elderly patients, ESD is an acceptable treatment for EGC in terms of both short- and long-term outcomes. Careful clinical assessment of elderly patients is necessary before ESD. After ESD, medical follow-up is important so that other malignancies and diseases that affect the elderly are not overlooked. |
| Databáze: | OpenAIRE |
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