Low stroke rate and few thrombo-embolic events after HeartMate II implantation under mild anticoagulation
| Autor: | Andreas Götzenich, Ares K. Menon, Helena Sassmannshausen, Rüdiger Autschbach, Jan Spillner, M Haushofer |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Gastrointestinal bleeding medicine.medical_treatment Thromboembolism medicine Humans Angiodysplasia Heart Failure Aspirin business.industry Heparin Anticoagulants General Medicine Middle Aged medicine.disease Thrombosis Surgery Transplantation Stroke Embolism Ventricular assist device Heart failure Phenprocoumon Female Heart-Assist Devices Cardiology and Cardiovascular Medicine business Destination therapy |
| Zdroj: | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 42(2) |
| ISSN: | 1873-734X |
| Popis: | OBJECTIVES: Bleeding and thrombo-embolism are two of the most threatening adverse events associated with the use of continuous flow left ventricular assist devices (LVADs) in the treatment of severe heart failure. We analysed our LVAD patients treated with the HeartMate II (HM II) device by following a low anticoagulation regimen. METHODS: Between 2008 and February 2011, we implanted 40 HM II LVADs in our institution. Intention to treat was bridge to transplant in 25, destination therapy in 9, bridge to candidacy in 5 cases and bridge to recovery in 1 case. Heparin was started only after 24 h postoperatively, and Phenprocumon (Phen) was started after removal of all chest drains. International normalized ratio (INR) target in the years 2008–2009 was 2.5, and 2.0–2.5 since 2010. Acetyl salicylic acid (ASA) was prescribed 50–100 mg/day only in patients |
| Databáze: | OpenAIRE |
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