Topography of MR lesions correlates with standardized EEG pattern in early comatose survivors after cardiac arrest
| Autor: | Matthias Haenggi, Rike Barth, Frédéric Zubler, Franca Wagner, Kaspar Schindler, Anja Weck, Roland Wiest |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty 610 Medicine & health 030204 cardiovascular system & hematology Emergency Nursing Electroencephalography Grey matter Eeg patterns Lesion 03 medical and health sciences 0302 clinical medicine Basal ganglia medicine Effective diffusion coefficient Humans In patient Survivors Coma medicine.diagnostic_test business.industry 030208 emergency & critical care medicine Prognosis Magnetic Resonance Imaging Heart Arrest medicine.anatomical_structure Emergency Medicine Radiology medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Barth, Rike; Zubler, Frederic; Weck, Anja; Haenggi, Matthias; Schindler, Kaspar; Wiest, Roland; Wagner, Franca (2020). Topography of MR lesions correlates with standardized EEG pattern in early comatose survivors after cardiac arrest. Resuscitation, 149, pp. 217-224. Elsevier 10.1016/j.resuscitation.2020.01.014 |
| DOI: | 10.7892/boris.139680 |
| Popis: | AIM Multimodal prognostication in comatose patients after cardiac arrest (CA) is complicated by the fact that different modalities are usually not independent. Here we set out to systematically correlate early EEG and MRI findings. METHODS 89 adult patients from a prospective register who underwent at least one EEG and one MRI in the acute phase after CA were included. The EEGs were characterized using pre-existent standardized categories (highly malignant, malignant, benign). For MRIs, the apparent diffusion coefficient (ADC) was computed in pre-defined regions. We then introduced a novel classification based on the topography of ADC reduction (MR-lesion pattern (MLP) 1: no lesion; MLP 2: purely cortical lesions; MLP 3: involvement of the basal ganglia; MLP 4 involvement of other deep grey matter regions). RESULTS EEG background reactivity and EEG background continuity were strongly associated with a higher MLP value (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|