Cytochrome P4501A1 polymorphisms in the Amerindian and Mestizo populations of Mexico
| Autor: | Raúl Izaguirre, Aurora de la Peña, Teresa Juárez-Cedillo, Joaquín Zúñiga, Guadalupe Hernández-Pacheco, José Manuel Fragoso, Julio Granados, Erick Ramírez, Gilberto Vargas-Alarcón |
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| Rok vydání: | 2005 |
| Předmět: |
Genetics
education.field_of_study Polymorphism Genetic Genotype Mexican mestizo Clinical Biochemistry Population Locus (genetics) Cell Biology General Medicine Biology Biochemistry Genetics Population Gene Frequency Neoplasms Healthy individuals Cytochrome P-450 CYP1A1 Indians North American Humans Genetic Predisposition to Disease Allele education Mexico Language |
| Zdroj: | Cell Biochemistry and Function. 23:189-193 |
| ISSN: | 1099-0844 0263-6484 |
| Popis: | Several polymorphisms in the CYP1A1 locus have been identified and their genotypes appear to exhibit population frequencies that depend on ethnicity. We studied two CYP1A1 polymorphic sites (position 4889 and 6235) in a group of 212 unrelated healthy individuals belonging to three different Mexican populations (106 Mexican Mestizos, 52 Teenek and 54 Mayos). Comparison among Mexican populations showed increased frequency of the *Ile allele (A on position 4889) in Mexican Mestizos when compared to Amerindians (p |
| Databáze: | OpenAIRE |
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