Evidence for a local effect of intracervical prostaglandin E2-gel
| Autor: | Ulf Ulmsten, Axel Forman, L. Wingerup, Jolán Bányai, Niels Uldbjerg |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Adolescent medicine.medical_treatment Uterus Stimulation Cervix Uteri Oxytocin Dinoprostone Andrology Uterine Contraction Pregnancy Pressure Humans Medicine Infusions Parenteral Prostaglandin E2 Cervix business.industry Prostaglandins E Myometrium Obstetrics and Gynecology Gestational age Abortion Induced Dilatation Pregnancy Trimester First medicine.anatomical_structure Anesthesia Female business Gels medicine.drug Prostaglandin E |
| Zdroj: | Forman, A, Ulmsten, U, Bányai, J, Wingerup, L & Uldbjerg, N 1982, ' Evidence for a local effect of intracervical prostaglandin E2-gel ', American Journal of Obstetrics and Gynecology, vol. 143, no. 7, pp. 756-60 . Aarhus University |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/0002-9378(82)90005-9 |
| Popis: | Udgivelsesdato: 1982-Aug-1 Eight primigravid women with a mean gestational age of 9.4 weeks (9 to 10 weeks) who were admitted for first-trimester abortion by dilatation and evacuation were preoperatively treated for 6 hours with either intravenous infusion of oxytocin or a strictly intracervical application of prostaglandin E2 (PGE2) in viscous gel. Myometrial activity was monitored by intrauterine pressure recording throughout the treatment. Contractile activity was more pronounced in the oxytocin-treated group, whereas cervical priming occurred after the PGE2 treatment only. Intracervical PGE2-gel is suggested to have direct effects on the cervical tissues, independent of uterine contractile activity. Furthermore, myometrial stimulation induced by escape of gel into the extra-amniotic space can be avoided by adjusting the volume of gel and technique of application to the dimensions of the cervix. |
| Databáze: | OpenAIRE |
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