Postoperative reorganization of gastric pacemaker activity in patients after an extended period following distal gastrectomy
| Autor: | Shinji Homma, Katsuyoshi Hatakeyama, Tatsuo Kanda, Haruhiko Okamoto, Manabu Ohashi, Shin-ichi Kosugi, Yasuo Kobayashi |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Physiology Period (gene) Distal gastrectomy Myocytes Smooth Muscle Postoperative recovery Quality of life Biological Clocks Gastrectomy Electrogastrogram medicine Humans In patient Aged Aged 80 and over medicine.diagnostic_test business.industry Stomach General Medicine Middle Aged Postprandial Period Electrophysiological Phenomena Surgery Gastrointestinal Tract Postprandial Anesthesia embryonic structures Power ratio Quality of Life Female business human activities Follow-Up Studies |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1884-8796 0916-8737 |
| DOI: | 10.1540/jsmr.44.113 |
| Popis: | We recorded and analyzed electrogastrograms (EGGs) from 12 patients following distal gastrectomy. The EGGs were recorded from between 3 and 262 months post-operatively. Gastric electrical activity, which showed a distinct repeating pattern with a frequency of 3 cycles per minute (cpm), was easily recognizable in subjects who were recorded 16-20 years postoperatively, but was not clearly evident in EGG running spectra of subjects with a shorter postoperative period. Although the postprandial instability factor of the 3-cpm components (standard deviation of mean spectral frequency of peak 3-cpm group/mean of the 3-cpm spectral frequency) of the epigastric and supraumbilical EGGs showed a significant negative linear correlation with postoperative months, no such correlation was seen in the postprandial to fasting power ratio (postprandial power / fasting power) of the 3-cpm activity component. Therefore, we hypothesized that the disorganized pacemaker activity of the remnant stomach following distal gastrectomy can be reorganized to work as a synchronized unit over a long postoperative recovery period of from 15 to 20 years. A greater degree of epigastric and supraumbilical fasting 6-cpm power seemed to result in a worse quality of life (QOL). Similarly, a larger ratio of the supraumbilical postprandial to fasting power ratio of the 6-cpm activity seemed to result in a worse QOL. In contrast a larger ratio of the infaraumbilical postprandial to fasting power content of the 6-cpm activity seemed to result in a better QOL. |
| Databáze: | OpenAIRE |
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