Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software: A case report
| Autor: | C. Hollmann, E. Coetzee, N. J. M. Enslin, Rebecca Gray, JF Coetzee |
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| Rok vydání: | 2019 |
| Předmět: |
business.industry
medicine.medical_treatment Remifentanil cervical limited dorsal myeloschisis intraoperative neuromonitoring (IONM) total intravenous anaesthesia (TIVA) target controlled infusion (TCI) paediatric anaesthesia Myeloschisis 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Pharmacokinetics Intravenous anesthesia 030202 anesthesiology Anesthesia medicine Airway management Alfentanil business Propofol 030217 neurology & neurosurgery Syringe medicine.drug |
| Zdroj: | Southern African Journal of Anaesthesia and Analgesia; Vol. 25 No. 6 (2019); 32-35 Publons |
| ISSN: | 2220-1173 2220-1181 |
| Popis: | We present an uncommon case of limited dorsal myeloschisis in a 3-month-old infant requiring repair guided by intraoperative neuromonitoring (IONM) and therefore avoidance of volatile anaesthetic agents. The case presented challenges in positioning, airway management, a lack of age appropriate pharmacokinetic models in target-controlled infusion (TCI) syringe pumps and unavailability of remifentanil, considered to be an essential drug in this setting. We overcame these challenges using manually controlled infusions of propofol and alfentanil guided by pharmacokinetic simulation software (Stelsim). |
| Databáze: | OpenAIRE |
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