IL-18 in pregnancy; the elevation of IL-18 in maternal peripheral blood during labour and complicated pregnancies
| Autor: | Yuko Nakata, Junko Muranaka, Susumu Adachi, Koji Koyama, Akinori Ida, Yoshiyuki Tsuji, Riichiro Kanazawa, Haruki Okamura |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Immunology Pain Prom Acute fatty liver of pregnancy Pregnancy medicine Humans Immunology and Allergy reproductive and urinary physiology Labor Obstetric Obstetrics business.industry Interleukin-18 Obstetrics and Gynecology medicine.disease female genital diseases and pregnancy complications Peripheral blood Pregnancy Complications First trimester Reproductive Medicine Gestation Female Interleukin 18 Pregnancy Trimesters business Premature rupture of membranes |
| Zdroj: | Journal of Reproductive Immunology. 47:65-74 |
| ISSN: | 0165-0378 |
| DOI: | 10.1016/s0165-0378(00)00058-9 |
| Popis: | Serum interleukin-18 (IL-18) levels were measured in women in different trimesters of pregnancy, in labour, puerperium and in various complicated pregnancies. There was a significant elevation of IL-18 levels in pregnant sera from the first trimester until the onset of labour. Once labour began, IL-18 levels increased further and remained until at least the third day of puerperium. The high levels of IL-18 in sera were also observed in various complicated pregnancies, such as premature rupture of membranes (PROM), acute fatty liver of pregnancy and fetal growth restriction. IL-18 is likely to play a role in pregnancy. |
| Databáze: | OpenAIRE |
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