Posttraining norepinephrine infusion into the central amygdala differentially enhances later retention in Roman high-avoidance and low-avoidance rats

Autor:	Roozendaal, B., Koolhaas, J.M., Bohus, B.
Rok vydání:	1993
Předmět:	INVOLVEMENT Behavioral Neuroscience SEROTONERGIC ACTIVITY BEHAVIORAL-RESPONSE STRESS RESPONSES MEMORY CATECHOLAMINE FOOTSHOCK EPINEPHRINE NORADRENERGIC SYSTEM NUCLEUS
Zdroj:	Behavioral Neuroscience, 107(4), 575-579
ISSN:	1939-0084 0735-7044
DOI:	10.1037/0735-7044.107.4.575
Popis:	Memory-enhancement effects of norepinephrine (NE) were investigated by infusing NE into the central amygdala (CEA) of Roman high-avoidance (RHA) and low-avoidance (RLA) rats after training on active and passive behaviors in the defensive-burying paradigm. During acquisition, both lines spent comparable time in burying behavior. RLA rats, but not RHA rats, also displayed substantial immobility. During retention, the cerebrospinal-fluid-treated RLA rats mostly displayed immobility to the nonelectrified probe, whereas the RHA rats showed neither burying nor immobility. In the RLA rats, high-dose (200 ng), but not low-dose (20 ng), NE infusion enhanced the duration of the passive response (immobility) without affecting the active response. NE given into the CEA of RHA rats caused a selective dose-dependent appearance of the active behavioral component. The results suggest a phenotype-dependent effect of intra-amygdaloid NE on memory processes in the rat.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bfcac428d4b13b2e863ea6850dae9e https://doi.org/10.1037/0735-7044.107.4.575 Zobrazit plný text záznamu