Ultrasensitive mycotoxin detection by STING sensors
| Autor: | Nader Pourmand, Olufisayo Jejelowo, Paolo Actis |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Detection limit
Analyte Materials science Conductometry Microchemistry Biomedical Engineering Biophysics Food Contamination Nanotechnology Biosensing Techniques Equipment Design General Medicine Mycotoxins Article Nanostructures Equipment Failure Analysis Sting Electrochemistry Biosensor Food Analysis Biotechnology Label free |
| Zdroj: | Biosensors and Bioelectronics. 26:333-337 |
| ISSN: | 0956-5663 |
| Popis: | Signal transduction by ion nano-gating (STING) technology is a label-free biosensor capable of identifying DNA and proteins. Based on a functionalized quartz nanopipette, the STING sensor includes specific recognition elements for analyte discrimination based on size, shape and charge density. A key feature of this technology is that it does not require any nanofabrication facility; each nanopipette can be easily, reproducibly, and inexpensively fabricated and tailored at the bench, thus reducing the cost and the turnaround time. Here, we show that STING sensors are capable of the ultrasensitive detection of HT-2 toxin with a detection limit of 100 fg/ml and compare the STING capabilities with respect to conventional sandwich assay techniques. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect