Chronic pesticide mixture exposure including paraquat and respiratory outcomes among Colombian farmers
| Autor: | David Combariza, Andrés A Monroy-García, Sonia M. Díaz-Criollo, Marcela E. Varona-Uribe, Marien Palma, Alvaro J. Idrovo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Paraquat Chronic exposure Spirometry Chest Pain Adolescent Health Toxicology and Mutagenesis Respiratory Tract Diseases Colombia Toxicology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Occupational Exposure Environmental health Humans Medicine 0501 psychology and cognitive sciences Pesticides Respiratory system Chemical mixtures 050107 human factors Aged Asthma Farmers medicine.diagnostic_test business.industry Methamidophos Organothiophosphates 05 social sciences Public Health Environmental and Occupational Health Organothiophosphorus Compounds Middle Aged Pesticide medicine.disease Rhinitis Allergic 030210 environmental & occupational health Occupational epidemiology chemistry Acute exposure Female Original Article business |
| Zdroj: | Industrial Health Repositorio EdocUR-U. Rosario Universidad del Rosario instacron:Universidad del Rosario |
| ISSN: | 1880-8026 0019-8366 |
| DOI: | 10.2486/indhealth.2018-0111 |
| Popis: | This study explored the potential association between chronic exposure to pesticide mixtures including paraquat and respiratory outcomes among Colombian farmers. Sociodemographic and occupational data, respiratory symptoms and spirometric data were collected. Paraquat in spot urine samples were quantified with solid-phase extraction high-performance liquid chromatography. Multiple Poisson regressions with robust variance were used to determine factors associated with respiratory outcomes. Profiles of pesticide mixtures used were identified among 217 farmwork-ers, but profenofos and methamidophos-based mixtures were more frequent. Chronic paraquat exposure was slightly associated with self-reported asthma (PR: 1.06; 95% CI 1.00 to 1.13). Different pesticide mixtures were associated with flu, thoracic pain, allergic rhinitis, and obstructive pattern in spirometry. Although acute exposure to paraquat is low among Colombian farmers participating in the study, associations between respiratory outcomes and chronic pesticide mixtures exposure including profenofos, methamidophos or glyphosate require further specific studies. © 2020 National Institute of Occupational Safety and Health. |
| Databáze: | OpenAIRE |
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