Pharmacological and toxicological health risk of food (herbal) supplements adulterated with erectile dysfunction medications
| Autor: | Predrag Putnik, Danijela Bursać Kovačević, Irena Žuntar, Josipa Kosić-Vukšić, Adela Krivohlavek, Daniel Granato |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Sildenafil 030232 urology & nephrology Avanafil 01 natural sciences Applied Microbiology and Biotechnology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine medicine Intensive care medicine Udenafil Mirodenafil business.industry 010401 analytical chemistry Lodenafil medicine.disease Tadalafil 0104 chemical sciences Erectile dysfunction chemistry Vardenafil food supplements for erectile dysfunction phosphodiesterase type 5 inhibitors (PDE5Is) adulterated sildenafil tadalafil vardenafil avanafil business Food Science medicine.drug |
| Zdroj: | Current Opinion in Food Science. 24:9-15 |
| ISSN: | 2214-7993 |
| DOI: | 10.1016/j.cofs.2018.10.012 |
| Popis: | Erectile dysfunction is one of the most common sexual disorders among men, with large number of patients worldwide. This is a multifactorial disease with (non)organic causes while main oral drugs for the treatment are phosphodiesterase type 5 inhibitors (PDE5Is). Currently, sildenafil, vardenafil, tadalafil, udenafil, mirodenafil, lodenafil and avanafil are used. Worldwide use of herbal and dietary supplements for alleviating this problem is on a rise, as many consumers perceive these products as ‘healthier’ and safer as compared to conventional pharmaceutical preparations. However, adulteration of food supplements with PDE5Is and/or its analogues is very common and represents serious public health concern. This review address the issues with pharmacological and toxicological health risks of food supplements adulterated with erectile dysfunction medications. |
| Databáze: | OpenAIRE |
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