Amino acid chelated iron versus an iron salt in the treatment of iron deficiency anemia with pregnancy: A randomized controlled study
Autor: | Hisham Haggag, Ahmed S. M. Ali, Wafaa Ramadan, Ghada Abdel Fattah Abdel Moety, Doaa S. Belal, Reham Fouad |
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Rok vydání: | 2017 |
Předmět: |
Adult
medicine.medical_specialty Gastroenterology Ferrous Fumarate Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Internal medicine medicine Humans Ferrous Compounds 030212 general & internal medicine Amino Acids Adverse effect 030219 obstetrics & reproductive medicine Anemia Iron-Deficiency medicine.diagnostic_test RED-CELL INDICES business.industry Pregnancy Complications Hematologic Obstetrics and Gynecology medicine.disease Abdominal Pain Trace Elements Reproductive Medicine Biochemistry Iron-deficiency anemia Tolerability Serum iron Female Hemoglobin business Constipation medicine.drug |
Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 210:242-246 |
ISSN: | 0301-2115 |
DOI: | 10.1016/j.ejogrb.2017.01.003 |
Popis: | The aim of this study was to compare the efficacy and tolerability of iron amino acid chelate (IAAC) and ferrous fumarate (FF) in treatment of iron deficiency anemia (IDA) with pregnancy.A total of 150 pregnant women having iron deficiency anemia (IDA) were randomized to receive either IAAC or FF for 12 weeks. Hemoglobin, red cell indices, serum iron, and serum ferritin were measured at baseline and then 4, 8, and 12 weeks after treatment. Adverse effects were questioned in both groups.The mean values of hemoglobin, red cell indices, serum iron, and serum ferritin were not significantly different between both groups after 12 weeks of treatment. However, the rise in hemoglobin level after 4, 8, and 12 weeks of treatment was significantly faster in the IAAC group (p=0.001). Constipation and abdominal colicky pain were significantly more common in the FF group (p=0.022 and 0.031 respectively).IAAC and FF are comparable in curing IDA with pregnancy; however, IAAC has the advantage of providing a faster rate of improvement of hemoglobin level and is better tolerated by the patients. |
Databáze: | OpenAIRE |
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