Solitary Fibrous Tumors in the Head and Neck: Comprehensive Review and Analysis
| Autor: | Joshua D. Brody, Miriam Enriquez, Luke Stanisce, Nathan A. Deckard, Yekaterina Koshkareva, Nadir Ahmad, Kristin Levin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Solitary fibrous tumor Pathology Review Paper business.industry medicine.disease Pathology and Forensic Medicine 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Pooled analysis Oncology Otorhinolaryngology Head and Neck Neoplasms 030220 oncology & carcinogenesis Solitary Fibrous Tumors Oral and maxillofacial surgery Medicine Humans Positive Surgical Margin business Head and neck |
| Zdroj: | Head Neck Pathol |
| Popis: | Solitary fibrous tumors (SFT) arising in the head and neck region are uncommon yet well-recognized entities. Their biologic behavior and management still need to be elucidated. Systematically reviewing all published cases of SFT involving the head and neck region since 1991, a pooled meta-analysis was conducted to evaluate various demographic and tumor characteristics. 587 SFT in the head and neck have been reported; 343 met pooled analysis inclusion criteria. 61% of cases presented as a new mass; 89% were painless. Median onset of symptoms prior to evaluation was 8 months. Pre-operative local invasion and malignant histological features (hemorrhage, necrosis, mitoses > 4/10 hpf) were not statistically associated with decreased recurrence-free survival. Positive surgical margins was the only factor associated with shorter recurrence-free survival (p |
| Databáze: | OpenAIRE |
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