Synthesis and characterization of [1-13C]-and d8-arachidonic acid

Autor:	Un Hoi Do, M. G. Sundaram, Robert W. Bryant, S. Ramachandran
Rok vydání:	1979
Předmět:	chemistry.chemical_compound Chromatography Chemistry Organic Chemistry Mass spectrum High mass Arachidonic acid Cell Biology Mass spectrometry Biochemistry Nuclear chemistry
Zdroj:	Lipids. 14:819-821
ISSN:	1558-9307 0024-4201
DOI:	10.1007/bf02533522
Popis:	Methyld 8- and [1-13C] 5,8,11,14-eicosatetraenoate (arachidonate) were prepared from a common synthetic precursor, 4,7,10,13-nonadecatetrayn-1-ol. The purified products were characterized by gas chromatography-mass spectrometry. Mass spectra oft-butyldimethylsilyl esters ofd 8-and [1-13C]-arachidonic acid showed a most intense [M-57]+ peak at high mass. The isotopic purity of methyl [1-13C] arachidonate was 99% and that of methyld 8-arachidonate was 56%. Whend 8-arachidonic acid was prepared by direct deuteration of 5,8,11,14-eicosatetraynoic acid, the isotopic purity of the sample was 86%.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a9a3cec0b16c33abc14fff68789778 https://doi.org/10.1007/bf02533522 Zobrazit plný text záznamu Full text from SpringerLink Plný text