Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study
| Autor: | Berk Gurpinar, Onur Üstün, Deniz Hanci, Dilara Zeybek, Hüseyin Altun, Yavuz Uyar |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Medicine (General)
Chemistry Cartilage N-butyl-cyanoacrylate General Medicine 2-Octyl cyanoacrylate Experimental animal chemistry.chemical_compound medicine.anatomical_structure R5-920 fibrin tissue adhesive cyanoacrylates Polymer chemistry medicine otorhinolaryngologic diseases Medicine Fibrin glue cartilage octyl 2-cyanoacrylate |
| Zdroj: | Haseki Tıp Bülteni, Vol 59, Iss 4, Pp 268-272 (2021) |
| ISSN: | 2147-2688 1302-0072 |
| Popis: | Aim:Following septoplasty surgery, nasal packing is performed to stabilize the healing of septum and prevent septal hematoma. The purpose of this study was to investigate the efficacy of fibrin glue, 2-octyl cyanoacrylate, and n-butyl cyanoacrylate on the healing of the septum cartilage following septoplasty.Methods:Since rabbit ear cartilages resemble septal cartilage, 10 New Zealand rabbits were used in our study which was performed between March and May 2016. A total of 20 ears of 10 rabbits were used, with 4 separate incisions in each ear. Perichondrial flaps were raised and the following chemical adhesives were applied separately on the cartilage: Fibrin glue, 2-octyl cyanoacrylate, n-butyl cyanoacrylate. As the control group, no material was applied to the remaining incision. The right ears were examined at 15 days and the left ears at 30 days; samples were removed with solid tissue around the edges, treated with formol and histopathologically examined.Results:Epithelial integrity and re-epithelialization were adequate in all groups. As the epithelium and perichondrium thicknesses were compared in the 15-day samples, epithelium and perichondrium were thicker in the n-butyl cyanoacrylate and 2-octyl cyanoacrylate groups than the other groups.Conclusion:N-butyl cyanoacrylate, fibrin glue and 2-octyl cyanoacrylate are potential alternatives for cartilage and mucosal support. |
| Databáze: | OpenAIRE |
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