Pulmonary Embolism
| Autor: | Arno Bücker, Süleyman Karaagac, Patrick Haage, Rolf W. Günther, Gabriele A. Krombach, Tobias Schäffter, Werner Piroth |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Swine Critical Care and Intensive Care Medicine Sensitivity and Specificity Magnetic resonance angiography Iodinated contrast Pulmonary angiography medicine Animals Observer Variation medicine.diagnostic_test business.industry Respiration Angiography Digital Subtraction Magnetic resonance imaging Gold standard (test) medicine.disease Magnetic Resonance Imaging Spiral computed tomography Pulmonary embolism Disease Models Animal Angiography Female Radiology Pulmonary Embolism business Nuclear medicine Tomography Spiral Computed Magnetic Resonance Angiography |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine. 167:729-734 |
| ISSN: | 1535-4970 1073-449X |
| Popis: | In the last decade, spiral computed tomography (CT) and magnetic resonance (MR) angiography (MRA) have become a viable alternative to conventional angiography in the diagnosis of acute pulmonary embolism. However, patients with dyspnea are often unable to hold their breath for a longer time and thus image degradation is frequently observed. Consequently, an imaging sequence that allows free breathing is desirable. The aim of this animal study was to compare contrast-enhanced spiral CT, MRA and a real-time MR sequence, the latter without breath-hold, with pulmonary angiography as reference gold standard. Nine pigs with artificially induced pulmonary embolism underwent this multimodality comparison. All images were independently evaluated for the presence of pulmonary emboli by two reviewers. Forty-three filling defects were detected by conventional angiography on lobar and segmental levels. Sensitivity of CT images was 72.1 and 69.8% for Readers 1 and 2, respectively, and sensitivity of MRA images was 79.1 and 81.4%. With real-time MR imaging, however, the detection rate was 97.7% for both readers. We conclude that, under experimental conditions, real-time MR imaging without the use of radiation or iodinated contrast material is comparable with angiography in the detection of pulmonary emboli. |
| Databáze: | OpenAIRE |
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