Perioperative outcomes of intracorporeal robot-assisted radical cystectomy versus open radical cystectomy: A systematic review and meta-analysis of comparative studies
| Autor: | Chaohui Gu, Fengyan Tian, Wei Lu, Long Chen, Yongjie Feng, Keyuan Zhao, Ruixin Fan, Naichun Zhou |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Blood transfusion business.industry medicine.medical_treatment Postoperative complication Retrospective cohort study Robotics General Medicine Perioperative Cochrane Library Cystectomy Surgery Postoperative Complications Treatment Outcome Robotic Surgical Procedures Urinary Bladder Neoplasms Meta-analysis medicine Humans Prospective Studies business Prospective cohort study Retrospective Studies |
| Zdroj: | International Journal of Surgery. 94:106137 |
| ISSN: | 1743-9191 |
| Popis: | To systematically review studies comparing the perioperative outcomes of intracorporeal robot-assisted radical cystectomy (iRARC) and open radical cystectomy (ORC).Systematic searches of PubMed, Web of Science and the Cochrane Library were performed in June 2020. Studies with data comparing iRARC and ORC were included in our review, and a pooled meta-analysis was completed.In total, 8 studies (7 prospective studies, 1 retrospective study) comparing 1193 patients were included for our review and meta-analysis. Compared with ORC, iRARC demonstrated lower estimated blood loss (weighted mean difference (WMD): -449.25; 95% CI -566.47 - -332.03; p 0.01), lower blood transfusion rates (OR: 0.31; 95% CI 0.22 - 0.46; p 0.01), and lower postoperative complication rates with Clavien-Dindo grades III-IV (30 days: OR: 0.65; 95% CI 0.47 - 0.90; p = 0.01; 90 days: OR: 0.72; 95% CI 0.53 - 0.98; p = 0.04), but a longer operative time (WMD: 78.82; 95% CI 52.77 - 104.87; P 0.01). Furthermore, there was no significant difference between iRARC and ORC in terms of postoperative complication rates with Clavien-Dindo grades Ⅰ-Ⅱ (30 days: OR: 0.71; 95% CI 0.36 - 1.40; p = 0.32; 90 days: OR: 0.98; 95% CI 0.74 - 1.30; p = 0.89), length of stay (WMD: -1.18; 95% CI -3.33 - -2.07; p = 0.06) and positive surgical margins (OR: 0.78; 95% CI 0.0.45 - 1.36; p = 0.38).iRARC was associated with a significantly lower estimated blood loss and a lower blood transfusion rate and major postoperative complication rate than ORC. |
| Databáze: | OpenAIRE |
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