Antimutagenic effects of the composition from green tea leaves extracts and Caucasian persimmon fruits

Autor:	N. A. Abdullaev, M. B. Guseinov
Rok vydání:	2021
Předmět:	chemistry.chemical_compound chemistry Concentration dependence Sodium fluoride Composition (visual arts) General Medicine Food science Green tea extract Green tea Antimutagen General Biochemistry Genetics and Molecular Biology Peripheral blood
Zdroj:	Bulletin of Experimental Biology and Medicine. 172:168-171
ISSN:	2413-1008 0365-9615
DOI:	10.47056/0365-9615-2021-172-8-168-171
Popis:	On a culture of human peripheral blood lymphocytes, antimutagenic activity of a composition from extracts of green tea leaves and Caucasian persimmon fruits was established with a modification of the mutation process induced by chemical compounds producing an alkylating effect (nitrosomethylurea and sodium fluoride). A concentration dependence of the antimutagenic efficiency of the studied phytocomposite was shown. The highest antimutagenic efficiency was observed when a combination of green tea extract at a concentration of 0.01 μg/ml and persimmon fruit extract at a concentration of 0.001 μg/ml were used. Moreover, this combination was most effective against mutations induced by both nitrosomethylurea and sodium fluoride: the antimutagen efficiency factor was 0.53 and 0.55, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249956ec9f2ce2349c3c7df2bb298086 https://doi.org/10.47056/0365-9615-2021-172-8-168-171 Zobrazit plný text záznamu