Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes
| Autor: | Sharon A. Baker-Zander, Jeanne M. Shaffer, Sheila A. Lukehart |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Immunology
urologic and male genital diseases Microbiology Immunoglobulin G Phagocytosis Antigen Leptospiraceae Animals Treponema pallidum Opsonin Treponema biology Immune Sera bacterial infections and mycoses biology.organism_classification Antibodies Bacterial Virology Antibody opsonization stomatognathic diseases Infectious Diseases biology.protein Parasitology Rabbits Borrelia hermsii Leptospira interrogans Research Article |
| Zdroj: | Infection and Immunity. 61:781-784 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.61.2.781-784.1993 |
| Popis: | Rabbit antisera to Leptospira interrogans, Borrelia hermsii, and Treponema phagedenis biotype Reiter, reactive to shared spirochetal antigens, failed to enhance phagocytosis of Treponema pallidum by macrophages, while immunoglobulin G to Treponema pallidum subsp. pertenue and Treponema paraluiscuniculi promoted phagocytosis. Opsonic antibodies are directed to pathogen-restricted, not shared spirochetal, antigens. |
| Databáze: | OpenAIRE |
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