Narcolepsy with cataplexy in patients aged over 60 years: a case-control study
| Autor: | Karel Sonka, Eva Topinkova, Petra Kovalská, David Kemlink, Eva Jarolímová, Soňa Nevšímalová, Eszter Maurovich Horvat |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Physical fitness Poison control Comorbidity Type 2 diabetes Statistics Nonparametric 03 medical and health sciences Cataplexy 0302 clinical medicine Quality of life Surveys and Questionnaires Humans Medicine 030212 general & internal medicine Depression (differential diagnoses) Aged Chi-Square Distribution Depression business.industry Age Factors Case-control study General Medicine Middle Aged medicine.disease Cross-Sectional Studies Diabetes Mellitus Type 2 Physical Fitness Case-Control Studies Chronic Disease Hypertension Physical therapy Female Geriatric Depression Scale business 030217 neurology & neurosurgery |
| Zdroj: | Sleep Medicine. 26:79-84 |
| ISSN: | 1389-9457 |
| Popis: | Objective Narcolepsy with cataplexy (NC) is a chronic disabling disease; however, there are insufficient data on older NC subjects. Methods A cross-sectional evaluation on health and social status, including intensity and progression of NC symptoms, was performed on 42 NC patients (age 71.9 years ± 7.5) and 46 age-and-sex-matched controls (age 72.2 years ± 7.0). Results A greater proportion of patients than controls suffered from hypertension and type 2 diabetes. More controls had a history of treated depression; however, according to the Geriatric Depression Scale, more NC patients scored in the range of depression. There were no significant differences in Addenbrook Cognitive Examination scores. Average physical fitness assessed by the Short Physical Performance Battery was lower in the NC group. The frequency of meeting with family, friends, and participation in hobbies or sports did not differ between the two groups. Conclusions Symptoms of NC were present throughout life. Comorbidities and lower physical fitness, which are known to be present in young and middle-aged NC subjects, were also present in older patients. Although NC subjects were less professionally active during their lifetime, they did not differ from controls in important social parameters in older age. |
| Databáze: | OpenAIRE |
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