Prevalence of Sarcopenia in Women with Breast Cancer
| Autor: | Delia Morlino, Maurizio Marra, Iolanda Cioffi, Lidia Santarpia, Pietro De Placido, Mario Giuliano, Carmine De Angelis, Simone Carrano, Annarita Verrazzo, Giuseppe Buono, Marianna Naccarato, Olivia Di Vincenzo, Enza Speranza, Sabino De Placido, Grazia Arpino, Fabrizio Pasanisi |
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| Přispěvatelé: | Morlino, Delia, Marra, Maurizio, Cioffi, Iolanda, Santarpia, Lidia, De Placido, Pietro, Giuliano, Mario, De Angelis, Carmine, Carrano, Simone, Verrazzo, Annarita, Buono, Giuseppe, Naccarato, Marianna, Di Vincenzo, Olivia, Speranza, Enza, De Placido, Sabino, Arpino, Grazia, Pasanisi, Fabrizio |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Cross-Sectional Studie
Adult body composition Sarcopenia Nutrition and Dietetics Hand Strength Breast Neoplasms Middle Aged breast cancer Cross-Sectional Studies sarcopenia bioimpedance analysis (BIA) hand grip strength (HGS) phase angle (PhA) Prevalence Humans Female human activities Breast Neoplasm Human Aged Food Science |
| Zdroj: | Nutrients; Volume 14; Issue 9; Pages: 1839 |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu14091839 |
| Popis: | Sarcopenia is a common finding in patients with cancer and potentially influences the patient’s outcome. The aim of this study was to evaluate the prevalence of sarcopenia, according to the European Working Group on Sarcopenia in Older People, in a sample of women with breast cancer (BC) and a BMI lower than 30 kg/m2. This cross-sectional study was conducted in patients with BC, stage 0-III, and receiving therapy for BC; the women were recruited at the Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy. A control group with similar age and BMI was selected from the internal database. Anthropometry, bioimpedance analysis (BIA) and hand grip strength (HGS) were measured to detect sarcopenia. A total of 122 patients (mean age 49.3 ± 11.0 years, BMI 24.6 ± 3.0 kg/m2) and 80 healthy controls were analyzed. Sarcopenia was found in 13.9% patients with BC, while none of the subjects in the control group was sarcopenic. By comparing BC patients with and without sarcopenia and the control group, the fat-free mass of sarcopenic BC patients were significantly lower than those of both non-sarcopenic BC patients and the control (p < 0.05). The phase angle was also significantly lower in sarcopenic patients (−0.5 degrees, p = 0.048) than in the control group. Considering the prevalence of sarcopenia in patients with BC, our findings suggest the usefulness of body composition and HGS evaluation for early screening of sarcopenia to reduce the risk of associated complications. |
| Databáze: | OpenAIRE |
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