Right ventricular function differs in idiopathic dilated versus ischemic cardiomyopathy

Autor: Olaf Grebe, Udo Classen, Kai Magnusson, Bernward Kurtz, Ernst G Vester, Stefan Schlueter
Jazyk: angličtina
Předmět:
Zdroj: Journal of Cardiovascular Magnetic Resonance, Vol 12, Iss Suppl 1, p M5 (2010)
ISSN: 1532-429X
DOI: 10.1186/1532-429x-12-s1-m5
Popis: Results The underlying cause for heart failure was in 52% coronary artery disease (CAD), mean LVEF was 26 ± 6%; RVEF 50 ± 13% in this subgroup. Mean LVEDVI (end-diastolic volume index) was markedly raised (118 ± 38 ml/m2), RVEDVI was normal (59 ± 20 ml/m2). 34% of the patients had idiopathic DCM, mean values for LVEF/EDVI and RVEF/EDVI were 24 ± 7%; p = 0.62 und 138 ± 36 ml/m2; p = 0.02 as well as 40 ± 13%; p < 0.01 and 77 ± 26 ml/m2; p < 0.01 as compared to CAD patients. The remaining patients other causes for LV functional impairment (restrictive, tachymyopathy, valvular disease). In 38% of the patients with ischemic cardiomyopathy pulmonary hypertension was present. In these cases significantly higher right ventricular volumes (65 ± 20 ml/m2 versus 54 ± 18 ml/m2; p = 0.03) und a lower RVEF (40 ± 13% versus 55 ± 10%; p < 0.01) could be measured in comparison to patients without a normal pressure in the pulmonary artery. In Patients with DCM, no significant differences of leftand right ventricular functional parameters in dependence of pulmonary disease could be found. However, Right ventricular EF was significantly correlated to LVEF in the DCM group (r = 0.77; p < 0.01), this was not found in the CAD group.
Databáze: OpenAIRE