Contrast sensitivity function in patients with beta-thalassemia major
| Autor: | N. Zoumbos, John X. Koliopoulos, Sotirios P. Gartaganis, Ephigenia K. Mela |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male medicine.medical_specialty Blood transfusion Adolescent medicine.medical_treatment media_common.quotation_subject Vision Disorders Deferoxamine Gastroenterology Contrast Sensitivity Internal medicine medicine Humans Contrast (vision) Blood Transfusion In patient Chelation therapy Sensitivity (control systems) Fluorescein Angiography media_common biology medicine.diagnostic_test business.industry beta-Thalassemia Beta thalassemia Middle Aged Fluorescein angiography medicine.disease Chelation Therapy Surgery Ferritin Ophthalmology Ferritins biology.protein Female business |
| Zdroj: | Acta Ophthalmologica Scandinavica. 78:512-515 |
| ISSN: | 1395-3907 |
| Popis: | Purpose: To investigate contrast sensitivity function in patients with beta-thalassemia major, after regular transfusion and chelation therapy. Methods: We measured contrast sensitivity at four spatial frequencies in 30 patients with beta-thalassemia major and in 30 matched normal control subjects. All subjects underwent an ophthalmic examination that included fluorescein angiography. The contrast sensitivity results from the two groups were compared between them. Patients' contrast sensitivity values were correlated to the variables age, duration of transfusion, duration of chelation therapy and serum ferritin levels, to select the important predictors. Results: Contrast sensitivity function in all beta-thalassemic patients was significantly lower (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|