Objectively assessed sleep-disordered breathing during pregnancy and infant birthweight

Autor: Grace W. Pien, Chia Ling Nhan-Chang, William A. Grobman, Francesca L. Facco, Jacob C. Larkin, Phyllis P Zee, Hyagriv N. Simhan, David M. Haas, Marquis Hawkins, Uma M. Reddy, Samuel Parry, Nichd NuMoM b, Judette Louis, Nathan R. Blue, Susan Redline, Robert C. Basner, Judith H. Chung, Robert M. Silver, Corette B. Parker
Rok vydání: 2021
Předmět:
Reproductive health and childbirth
Abnormal fetal growth
Hypoxemia
Cohort Studies
0302 clinical medicine
Pregnancy
Psychology
Birth Weight
Lung
Pediatric
Obstetrics
Incidence (epidemiology)
Nocturnal hypoxemia
Gestational age
Sleep apnea
General Medicine
Mental Health
Infant
Small for Gestational Age
symbols
Gestation
Female
medicine.symptom
Sleep Research
medicine.medical_specialty
Clinical Sciences
Gestational Age
Article
03 medical and health sciences
symbols.namesake
Sleep Apnea Syndromes
Clinical Research
medicine
NICHD NuMoM2b and NHLBI NuMoM2b Heart Health Study Networks
Humans
Poisson regression
Sleep-disordered breathing
Neurology & Neurosurgery
business.industry
Prevention
Infant
Newborn
Infant
Newborn
medicine.disease
nervous system diseases
respiratory tract diseases
030228 respiratory system
Relative risk
Small for Gestational Age
business
030217 neurology & neurosurgery
Zdroj: Sleep Med
ISSN: 1389-9457
DOI: 10.1016/j.sleep.2021.02.043
Popis: BackgroundSleep-disordered breathing (SDB) in pregnancy is associated with adverse maternal outcomes. The relationship between SDB and infant birthweight is unclear. This study's primary aim is to determine if objectively measured SDB in pregnancy is associated with infant birthweight.MethodsWe measured SDB objectively in early (6-15 weeks' gestation) and mid (22-31 weeks' gestation) pregnancy in a large cohort of nulliparous women. SDB was defined as an Apnea-Hypopnea Index ≥5 and in secondary analyses we also examined measures of nocturnal hypoxemia. We used a modified Poisson regression approach to estimate relative risks (RR) of large-for-gestational-age (LGA: >90th percentile for gestational age) and small-for-gestational-age (SGA
Databáze: OpenAIRE
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