Measuring pulse wave velocity with a novel, simple sensor on the fingertip: a feasibility study in healthy volunteers
| Autor: | Sjoerd P. Niehof, Marit H. N. van Velzen, Arjo J. Loeve, Egbert G. Mik |
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| Přispěvatelé: | Anesthesiology |
| Rok vydání: | 2019 |
| Předmět: |
0206 medical engineering
Flow mediated dilation Photoplethysmography (PPG) 02 engineering and technology 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Measurement device endothelial function Photoplethysmogram Healthy volunteers Medicine flow-mediated dilation cardiovascular diseases Reactive hyperemia Pulse wave velocity General Nursing business.industry pulse wave velocity (PWV) 020601 biomedical engineering Clinical Practice cardiovascular system business Vasomotor tone Biomedical engineering circulatory and respiratory physiology |
| Zdroj: | Biomedical Physics & Engineering Express, 5(6):Unsp 065010. IOP Publishing Ltd. Biomedical Physics & Engineering Express, 5(6) |
| ISSN: | 2057-1976 |
| Popis: | Objective: The speed of pressure pulses traveling through the blood, the pulse wave velocity (PWV), is a metric that provides substantial information about the passive and active elasticity of the blood vessels. Therefore, PWV is a valuable parameter in the diagnosis of cardiovascular and vessel-related neurological diseases. The purpose of this study was to investigate whether a novel, simple, easy-to-use, photoplethysmography-based Multi Photodiode Array (MPA) provides PWV measurements that agree with measurements done with more complicated and harder-to-use systems currently used in clinical practice. Methods: An often-used vascular perturbation that changes the conduit artery vasomotor tone during reactive hyperemia was imposed on thirty healthy volunteers. The MPA was used alongside and its results compared to those of a commonly used measurement device, the Biopac-system, during flow-mediated dilation (FMD). This way it was investigated if measurements with these systems, measuring over two different, but partly overlapping vessel trajectories agree. Results: The baseline absolute PWV values were significantly lower for the MPA as compared to the Biopac-system. Additionally, Bland-Altman plots and Pearson's correlation tests suggested good agreement between the two PWV measurement techniques during the FMD. Conclusion: Measuring PWV with the MPA in clinical practice is feasible and provides reliable data. Significance: The MPA may substantially simplify PWV measurements and may enable long-term PWV monitoring as long as one is aware of the relation between PWV and the vascular trajectory over which it is measured. |
| Databáze: | OpenAIRE |
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