Treatment interruption in HIV-positive patients followed up in Cameroon's antiretroviral treatment programme : individual and health care supply-related factors (ANRS-12288 EVOLCam survey)
| Autor: | Christelle, Tong, Marie, Suzan-Monti, Luis, Sagaon-Teyssier, Mohamed, Mimi, Christian, Laurent, Gwenaëlle, Maradan, Marie-Thérèse, Mengue, Bruno, Spire, Christopher, Kuaban, Laurent, Vidal, Sylvie, Boyer, I, Seyep |
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| Přispěvatelé: | Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Observatoire régional de la santé Provence-Alpes-Côte d'Azur [Marseille] (ORS PACA), Institut de Recherche pour le Développement (IRD), Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes (TransVIHMI), Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Université Catholique d'Afrique Centrale - Institut Catholique de Yaoundé (UCAC), Department of Internal Medicine and Subspecialties [Yaoundé, Cameroon], University of Yaoundé [Cameroun], This study was approved by the Cameroonian Ministry of Public Health and was financially supported by the French National Agency for Research on AIDS and viral hepatitis (ANRS)., EVOL Cam group, Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques er émergentes (TransVIHMI), Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Université Montpellier 1 (UM1), Lissalde, Claire |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Program evaluation medicine.medical_specialty Health Knowledge Attitudes Practice Tuberculosis Cross-sectional study Anti-HIV Agents [SDV]Life Sciences [q-bio] Developing country HIV Infections interruption du traitement antirétroviral antiretroviral treatment interruption health care supply-related factors Logistic regression Lower risk Health Services Accessibility 03 medical and health sciences 0302 clinical medicine Antiretroviral Therapy Highly Active Health care Medicine Humans 030212 general & internal medicine Cameroon [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology business.industry 1. No poverty Public Health Environmental and Occupational Health VIH HIV facteurs liés à l'offre des soins de santé Patient Acceptance of Health Care individual factors medicine.disease facteurs individuels 030112 virology 3. Good health [SDV] Life Sciences [q-bio] Infectious Diseases Cross-Sectional Studies Family medicine [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Population study Patient Compliance Parasitology business [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | Tropical Medicine & International Health Tropical Medicine & International Health, 2018, 23 (3), pp.315-326. ⟨10.1111/tmi.13030⟩ Tropical Medicine & International Health, John Wiley & Sons Ltd, 2018, 23 (3), pp.315-326. ⟨10.1111/tmi.13030⟩ |
| DOI: | 10.1111/tmi.13030⟩ |
| Popis: | International audience; introduction Decreasing international financial resources for HIV and increasing numbers of antiretroviral treatment (ART)-treated patients may jeopardise treatment continuity in low-income settings. Using data from the EVOLCam ANRS-12288 survey, this study aimed to document the prevalence of unplanned treatment interruption for more than 2 consecutive days (TI>2d) and investigate the associated individual and health care supply-related factors within the Cameroonian ART programme. methods A cross-sectional mixed methods survey was carried out between April and December 2014 in 19 HIV services of the Centre and Littoral regions. A multilevel logistic model was estimated on 1885 ART-treated patients in these services to investigate factors of TI>2d in the past 4 weeks. results Among the study population, 403 (21%) patients reported TI>2d. Patients followed up in hospitals reporting ART stock-outs were more likely to report TI>2d while those followed up in the Littoral region, in medium-or small-sized hospitals and in HIV services proposing financial support were at lower risk of TI>2d. The following individual factors were also associated with a lower risk of TI>2d: living in a couple, having children, satisfaction with attention provided by doctor, tuberculosis co-infection and not having consulted a traditional healer. conclusions Besides identifying individual factors of TI>2d, our study highlighted the role of health care supply-related factors in shaping TI in Cameroon's ART programme, especially the deleterious effect of ART stock-outs. Our results also suggest that the high proportion of patients reporting TI could jeopardise progress in the fight against HIV in the country, unless effective measures are quickly implemented like ensuring the continuity of ART supply. keywords HIV, Cameroon, antiretroviral treatment interruption, individual factors, health care supply-related factors |
| Databáze: | OpenAIRE |
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