Electrospinning chitosan/poly(ethylene oxide) solutions with essential oils: Correlating solution rheology to nanofiber formation
| Autor: | Nathan P. Birch, Jessica D. Schiffman, Katrina A. Rieger |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Polymers and Plastics
Oxide Nanofibers 02 engineering and technology 010402 general chemistry 01 natural sciences Cinnamaldehyde Polyethylene Glycols Chitosan chemistry.chemical_compound Polymer chemistry Materials Chemistry Oils Volatile Technology Pharmaceutical Acrolein chemistry.chemical_classification Ethylene oxide Chemistry Viscosity Organic Chemistry technology industry and agriculture Polymer 021001 nanoscience & nanotechnology Electrospinning 0104 chemical sciences Hydrophobe Molecular Weight Solutions Chemical engineering Nanofiber Alcohols 0210 nano-technology Rheology Hydrophobic and Hydrophilic Interactions |
| Zdroj: | Carbohydrate polymers. 139 |
| ISSN: | 1879-1344 |
| Popis: | Electrospinning hydrophilic nanofiber mats that deliver hydrophobic agents would enable the development of new therapeutic wound dressings. However, the correlation between precursor solution properties and nanofiber morphology for polymer solutions electrospun with or without hydrophobic oils has not yet been demonstrated. Here, cinnamaldehyde (CIN) and hydrocinnamic alcohol (H-CIN) were electrospun in chitosan (CS)/poly(ethylene oxide) (PEO) nanofiber mats as a function of CS molecular weight and degree of acetylation (DA). Viscosity stress sweeps determined how the oils affected solution viscosity and chain entanglement (Ce) concentration. Experimentally, the maximum polymer:oil mass ratio electrospun was 1:3 and 1:6 for CS/PEO:CIN and:H-CIN, respectively; a higher chitosan DA increased the incorporation of H-CIN only. The correlations determined for electrospinning plant-derived oils could potentially be applied to other hydrophobic molecules, thus broadening the delivery of therapeutics from electrospun nanofiber mats. |
| Databáze: | OpenAIRE |
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