A Pictorial Essay of Immunotherapy: Complications that Internists Will See, Whether They Like it or Not
| Autor: | Kenneth Gage, Trevor Rose, Ashley Evens, George Cyriac, Cyrillo Araujo, Daniel Jeong |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Lung Diseases
medicine.medical_specialty Variable manifestations Heart Diseases medicine.medical_treatment 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Immune system Diabetes mellitus Neoplasms medicine Humans 030212 general & internal medicine Intensive care medicine Adverse effect Organ system Brain Diseases Multiple cancer business.industry Cancer General Medicine Immunotherapy medicine.disease business |
| Zdroj: | The American journal of medicine. 132(7) |
| ISSN: | 1555-7162 |
| Popis: | Immunotherapy agents for treatment of cancer have been investigated for decades, but effective agents have only recently been identified and are increasingly being used in multiple cancer types. There is growing recognition of adverse side effects in multiple organ systems mediated by dysregulation of the immune system, which can be exacerbated by comorbidities often found in cancer patients such as chronic lung disease, diabetes, and hypertension. As a result, internists and other nononcology clinicians are routinely encountering immunotherapy patients who present with a remarkably wide range of symptoms. Here, we present the radiographic manifestations of common side effects from immunotherapy agents. An accurate diagnosis is critical in these often-complex clinical settings in which the consequences of the underlying cancer and other comorbidities must be distinguished from the variable manifestations of treatment toxicity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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