Clarifying the mechanism of idiopathic macular hole development in fellow eyes using spectral-domain optical coherence tomography
| Autor: | Mikiko Takezawa, Hiroko Yamagami, Fumihiko Toyoda, Akihiro Kakehashi, Chiho Kambara |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
optical coherence tomography idiopathic macular hole medicine.diagnostic_test genetic structures fellow eye business.industry posterior vitreous detachment Spectral domain Clinical Ophthalmology medicine.disease Posterior vitreous detachment eye diseases Ophthalmology Optical coherence tomography medicine Optometry sense organs business Macular hole Original Research |
| Zdroj: | Clinical Ophthalmology (Auckland, N.Z.) |
| ISSN: | 1177-5483 |
| Popis: | Mikiko Takezawa, Fumihiko Toyoda, Chiho Kambara, Hiroko Yamagami, Akihiro KakehashiDepartment of Ophthalmology, Jichi Medical University, Saitama Medical Center, Saitama, JapanBackground: To clarify the mechanism of idiopathic macular hole development, we evaluated the vitreoretinal relationship in fellow eyes of those with a macular hole and normal eyes using spectral-domain optical coherence tomography. Thirty-one fellow eyes and 34 normal volunteer eyes without a posterior vitreous detachment (PVD) were included.Results: We classified six vitreomacular relationships: type 1, no PVD, five fellow eyes (16.1%) and nine control eyes (26.5%); type 2, shallow PVD with perifoveal vitreous attachment, seven fellow eyes (22.6%) and 19 control eyes (55.9%); type 3, shallow PVD with pinpoint foveal vitreous traction, seven fellow eyes (22.6%) and no control eyes (0%), type 4a; shallow PVD with a round defect in the posterior vitreous cortex over the perifoveal area with vitreous attachment to the perifoveal area, two fellow eyes (6.5%) and one control eye (2.9%); type 4b, shallow PVD with a round defect in the posterior vitreous cortex over the perifoveal area without vitreous attachment to the perifoveal area, no fellow eyes (0%) and one control eye (2.9%); type 5a, shallow PVD with no pseudo-operculum, no fellow eyes (0%) and four control eyes (11.8%); type 5b, shallow PVD with a pseudo-operculum, four fellow eyes (12.9%) and no control eyes (0%); and type 6, biomicroscopically relevant PVD, six fellow eyes (19.4%).Conclusion: Types 3 and 5b developed only in fellow eyes. Type 2 developed most often in normal eyes and seemed to cause less foveal stress. Type 3 may show the basic pathogenesis of macular holes. Progression of type 5b after type 3 induces abortion of developing macular holes.Keywords: idiopathic macular hole, optical coherence tomography, posterior vitreous detachment, fellow eye |
| Databáze: | OpenAIRE |
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