Screening of Bioactive Compounds of Medicinal Mushrooms Collected on Tunisian Territory
Autor: | Ayda Khadhri, Chedia Aouadhi, Samira Aschi-Smiti |
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Rok vydání: | 2017 |
Předmět: |
Tunisia
DPPH Flavonoid Drug Evaluation Preclinical Applied Microbiology and Biotechnology Antioxidants chemistry.chemical_compound 0404 agricultural biotechnology Anti-Infective Agents Drug Discovery Tannin Fruiting Bodies Fungal Trametes versicolor Pharmacology chemistry.chemical_classification Biological Products Traditional medicine biology Basidiomycota 04 agricultural and veterinary sciences biology.organism_classification 040401 food science chemistry Proanthocyanidin Polyphenol Anthocyanin Agaricales Fomes fomentarius |
Zdroj: | International Journal of Medicinal Mushrooms. 19:127-135 |
ISSN: | 1521-9437 |
DOI: | 10.1615/intjmedmushrooms.v19.i2.40 |
Popis: | This study is, to our knowledge, the first to investigate the pharmacological importance of wild Tunisian mushrooms. Ethanolic extracts of 5 Tunisian mushrooms-Phellinus torulosus, Fomes fomentarius, Trametes versicolor, Pisolithus albus, and Fomitopsis pinicola-were collected from the Kroumirie Region (North Tunisia). The dry basidomes of mushrooms were extracted using ethanol and evaluated for total polyphenol, flavonoid, flavonol, tannin, proanthocyanidin, and anthocyanin content. In addition, their antioxidant activities were determined using 3 assays (testing 2,2-diphenyl-1-picrylhydrazyl [DPPH] radical scavenging, the reducing power of iron, and the iron-chelating power). Their antimicrobial activities were assessed against 8 bacterial species. The results revealed the presence of significant differences between the secondary metabolites and biological activities of the different tested extracts. In addition, significant correlations were observed between antioxidant activities and phenolic contents. Crude ethanol extracts prepared from basidomes of F. fomentarius and Ph. torulosus have higher total phenolic content and antioxidant activity per the DPPH and metal-chelating activity assays. The reducing power assay showed that the ethanolic extract of F. pinicola had the highest activity. Ethanolic extracts of the 5 mushrooms have antibacterial activity against the evaluated strains. |
Databáze: | OpenAIRE |
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