Chronotropic incompetence to exercise separates low body weight from established anorexia nervosa
| Autor: | David Duverney, L. Millot, Martin Garet, Frédéric Costes, Myriam Kadem, Jean-Claude Barthélémy, Vincent Pichot, Frédéric Roche, Bruno Estour |
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| Rok vydání: | 2004 |
| Předmět: |
Chronotropic
Adult Male Sympathetic nervous system medicine.medical_specialty Anorexia Nervosa Physiology Physical exercise Sensitivity and Specificity Diagnosis Differential Thinness Weight loss Physiology (medical) Internal medicine Heart rate medicine Heart rate variability Humans Diagnosis Computer-Assisted business.industry Reproducibility of Results General Medicine Autonomic nervous system medicine.anatomical_structure Endocrinology Ambulatory Cardiology Electrocardiography Ambulatory Exercise Test Female medicine.symptom business |
| Zdroj: | Clinical physiology and functional imaging. 24(5) |
| ISSN: | 1475-0961 |
| Popis: | Chronotropic incompetence (CI), characterized by an attenuated heart rate (HR) response to exercise could participate to the limitation of exercise capacity in anorexia nervosa (AN). Therefore, we evaluated the role of cardiac sympathetic responsiveness in AN patients. In addition, the ambulatory value of autonomic control using spectral analysis of heart rate variability (HRV) was determined and correlated to maximal exercise performance. Twenty-two patients hospitalized for weight loss and suspicion of AN were included in the study. All performed a symptom-limited exercise test with measurement of gas exchange for chronotropic response to exercise evaluation. Holter ECG recordings allowed daytime and night-time spectral domain HRV analysis in order to evaluate the alteration of sympathetic control of HR in free-living conditions. CI defined as a failure to achieve 80% of heart rate reserve (%HRR) was observed in 13 (59%) patients (CI+). This group presented a higher body mass deficit than the group without CI (CI-; -35.1 +/- 8.7% versus -26.1 +/- 10.7%; P |
| Databáze: | OpenAIRE |
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