Facilitative effects of VNS on the motor threshold: implications for its antidepressive mode of action?
| Autor: | Johannes Kornhuber, Helge H. Müller, Juan Manuel Maler, Wolfgang Sperling, Udo Reulbach |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Neurology Vagus Nerve Stimulation medicine.medical_treatment Stimulation medicine Humans Mode of action Biological Psychiatry Motor threshold Depressive Disorder Major Neurogenesis Middle Aged Evoked Potentials Motor medicine.disease Transcranial Magnetic Stimulation Transcranial magnetic stimulation Psychiatry and Mental health Major depressive disorder Female Neurology (clinical) Psychology Neuroscience Vagus nerve stimulation |
| Zdroj: | Journal of Neural Transmission. 120:1507-1510 |
| ISSN: | 1435-1463 0300-9564 |
| Popis: | In the present study, the effects of vagus nerve stimulation (VNS) on the resting motor threshold (rMT) of patients treated with repetitive transcranial magnetic stimulation were evaluated. Patients showed a significant decrease in the rMT during VNS-on stimulation. VNS was the only significant factor affecting rMT changes and did not appear to be a static variable. Further studies should focus on the effect of VNS on neural neurogenesis in depressive disorders, and the effects of other treatment options for major depressive disorder on the rMT should also be determined. |
| Databáze: | OpenAIRE |
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