Systemic High-sensitivity C-reactive Protein Levels in Normal-tension Glaucoma and Primary Open-angle Glaucoma
| Autor: | Wan-Jing Ho, Shirley H. L. Chang, Wei-Wen Su, Shih-Tsung Cheng, Shiu-Chen Wu |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty genetic structures Open angle glaucoma Glaucoma Blood Pressure Body Mass Index Heart Rate Normal tension glaucoma Internal medicine medicine Humans Intraocular Pressure medicine.diagnostic_test biology business.industry C-reactive protein Middle Aged medicine.disease Lipids eye diseases Ophthalmology C-Reactive Protein Blood pressure Cardiology biology.protein Female Ocular Hypertension sense organs Lipid profile business Body mass index Glaucoma Open-Angle Blood sampling |
| Zdroj: | Journal of Glaucoma. 16:320-323 |
| ISSN: | 1057-0829 |
| DOI: | 10.1097/ijg.0b013e3180391a83 |
| Popis: | PURPOSE To determine the systemic high-sensitivity C-reactive protein (hsCRP) level in patients with normal tension glaucoma (NTG) and primary open-angle glaucoma (POAG). MATERIALS AND METHODS With the exclusion of patients with cardiovascular and other systemic diseases, 40 patients with NTG, 40 with POAG, and 40 normal controls were enrolled in this study. Each patient underwent blood sampling for hsCRP, biochemistry, and lipid profile analysis. RESULTS Each group had similar demographic parameters including the age, sex, body mass index, heart rate, and blood pressure. There was no statistically significant difference in the hsCRP and biochemistry results between the 3 groups. The lipid profile exhibited a mild elevation in the patients with POAG. CONCLUSIONS Our data revealed no difference in the hsCRP level between NTG, POAG, and normal controls after exclusion of patients with cardiovascular and other systemic diseases. Systemic vascular inflammation may not be a major cause in the pathogenesis of glaucoma in those without histories of cardiovascular diseases. |
| Databáze: | OpenAIRE |
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