Treatment and chemoprevention of NSAID-associated gastrointestinal complications
| Autor: | Mae F Go, Edward J Frech |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Chemical Health and Safety peptic ulcer disease business.industry NSAIDs General Medicine Disease RM1-950 Review medicine.disease gastrointestinal prophylaxis digestive system diseases Gastrointestinal complications Peptic ulcer medicine Pharmacology (medical) Therapeutics. Pharmacology General Pharmacology Toxicology and Pharmaceutics business Intensive care medicine Safety Research Medical therapy |
| Zdroj: | Therapeutics and Clinical Risk Management Therapeutics and Clinical Risk Management, Vol 2009, Iss default, Pp 65-73 (2008) |
| ISSN: | 1178-203X 1176-6336 |
| Popis: | Edward J Frech1,2, Mae F Go1,21GI Section, George E Wahlen Department of Veterans Affairs Medical Center; 2Division of Gastroenterology, University of Utah School of Medicine, Salt Lake City, Utah, USAAbstract: The use of non-steroidal anti-inflammatory drugs has become ubiquitous worldwide and remains a common source of gastrointestinal morbidity. Antisecretory medications, particularly proton pump inhibitors, are effective in the treatment and prevention of NSAID-related gastrointestinal complications, including peptic ulcer disease and non-ulcer dyspepsia. A careful assessment of patients’ risk factors for developing NSAID-related gastrointestinal complications should be undertaken prior to initiation of any NSAIDs. Patients who are considered at risk for developing gastrointestinal complications should receive concurrent antisecretory medical therapy to minimize the risk for GI complications.Keywords: NSAIDs, peptic ulcer disease, gastrointestinal prophylaxis |
| Databáze: | OpenAIRE |
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