Alterations in the Baroreceptor-Heart Rate Reflex in Conscious Inbred Polydipsic (STR/N) Mice
| Autor: | B R Cui, C P Chu, Hiroshi Kannan, De-Lai Qiu |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Nitroprusside congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Baroreceptor Physiology Vasodilator Agents Blood Pressure Pressoreceptors Mice Phenylephrine Heart Rate Internal medicine Heart rate medicine Animals Vasoconstrictor Agents Polydipsia Mice Inbred ICR business.industry social sciences General Medicine Baroreflex Angiotensin II eye diseases humanities Endocrinology Blood pressure Anesthesia Reflex Sodium nitroprusside medicine.symptom business geographic locations medicine.drug |
| Zdroj: | Physiological Research. :173-182 |
| ISSN: | 1802-9973 0862-8408 |
| DOI: | 10.33549/physiolres.932820 |
| Popis: | STR/N is an inbred strain of mice which is known to exhibit extreme polydipsia and polyuria. We previously found central administration of angiotensin II enhanced cardiovascular responses in STR/N mice than normal mice, suggesting that STR/N mice might exhibit different cardiovascular responses. Therefore, in this study, we investigated daily mean arterial blood pressure and heart rate, and changes in the baroreceptor-heart rate reflex in conscious STR/N mice and control (ICR) mice. We found that variability in daily mean arterial blood pressure and heart rate was significantly larger in STR/N mice than in ICR mice (p |
| Databáze: | OpenAIRE |
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