Effect of bromhexine on the incidence of postoperative bronchopneumonia after upper abdominal surgery

Autor: E.J.B. Makin, K.N.V. Palmer, S.A. Hargrave
Rok vydání: 1975
Předmět:
Zdroj: British journal of diseases of the chest. 69
ISSN: 0007-0971
Popis: The incidence of postoperative bronchopneumonia in 70 patients undergoing upper abdominal surgery who received intramuscular and oral bromhexine after operation for 5 days was 25% (8 of 32), compared with 34% (13 of 38) in a control group, but this difference in favour of bromhexine does not reach statistical significance. All patients had postoperative physiotherapy. However, in a high-risk group (patients who smoked more than 10 cigarettes a day, who admitted to a productive cough before the operation and in whom the forced expiratory volume as a percentage of the forced vital capacity was less than 70) the incidence of postoperative bronchopneumonia in those who had bromhexine was 6 of 17 compared with 9 of 15 in the controls. Thus bromhexine for the prevention and treatment of postoperative bronchopneumonia in high-risk patients after upper abdominal surgery deserves further study.
Databáze: OpenAIRE