Simultaneous Estimation of Four Plasma Androgens Before and After Dynamic Tests in Women with Hirsutism: Correlation with Long-Term Therapy
| Autor: | A. Marocchi, G. Concolino, C. Conti, Sorcini G, V. Toscano, F. Sciarra |
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| Rok vydání: | 1976 |
| Předmět: |
Adult
Male Hirsutism medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Dexamethasone Correlation Sex Factors Endocrinology Estradiol Congeners Internal medicine Androstenediols medicine Humans Testosterone Long term therapy hirsutism Progesterone Congeners business.industry Androstenedione Dihydrotestosterone Middle Aged medicine.disease Androgens Female business medicine.drug |
| Zdroj: | Hormone Research. 7:16-27 |
| ISSN: | 1423-0046 0301-0163 |
| DOI: | 10.1159/000178704 |
| Popis: | Concentrations of testosterone, delta4-androstenedione, dihydrotestosterone and delta5-androstenediol were measured in 12 patients affected by hirsutism associated with menstrual disorders. Testosterone was elevated in 9 cases, in whom high levels of delta4-androstenedione and dihydrotestosterone was found, and normal in 3 cases, 2 of which presented high values of dihydrotestosterone and one high levels of delta5-androstenediol. In some hirsute females therefore, other androgens, such as dihydrotestosterone and delta5-androstenediol, play a role in the pathogenesis of hirsutism. Dexamethasone and estrogen progestin combinations were administered for dynamic tests, and results in most cases provided useful information in the selection of suitable long-term therapy. |
| Databáze: | OpenAIRE |
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