Mechanistic divergence of two closely related aldol-like enzyme-catalysed reactions
| Autor: | Emily J. Parker, Amy L. Pietersma, Linley R. Schofield, Meekyung Ahn |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
chemistry.chemical_classification
Aldehydes Binding Sites ATP synthase biology Threose Molecular Structure Stereochemistry Organic Chemistry Neisseria meningitidis Biochemistry Catalysis chemistry.chemical_compound Kinetics Enzyme Aldol reaction chemistry biology.protein 3-Deoxy-7-Phosphoheptulonate Synthase Physical and Theoretical Chemistry Aldehyde-Lyases |
| Zdroj: | Organicbiomolecular chemistry. 3(22) |
| ISSN: | 1477-0520 |
| Popis: | The analysis of the interaction of threose 4-phosphate and 2-deoxyerythrose 4-phosphate with 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAH7PS) reveals previously unrecognised mechanistic differences between the DAH7PS-catalysed reaction and that catalysed by the closely related enzyme, 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS). |
| Databáze: | OpenAIRE |
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