Medium-grade tubular proteinuria is common in HIV-positive patients and specifically associated with exposure to tenofovir disoproxil Fumarate
| Autor: | A. J. Zeder, Ulrich Seybold, R. Hilge, S. Y. Schrader, Johannes R. Bogner |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Adult Male medicine.medical_specialty Adolescent Anti-HIV Agents Renal function HIV Infections urologic and male genital diseases Gastroenterology 03 medical and health sciences chemistry.chemical_compound Young Adult 0302 clinical medicine Risk Factors Internal medicine Diabetes mellitus Germany medicine Prevalence Albuminuria Humans 030212 general & internal medicine Prospective cohort study Tenofovir Aged Aged 80 and over Creatinine Proteinuria urogenital system business.industry HIV General Medicine Middle Aged medicine.disease 030112 virology female genital diseases and pregnancy complications Infectious Diseases Cross-Sectional Studies Tubular proteinuria chemistry Female medicine.symptom business Kidney disease |
| Zdroj: | Infection. 44(5) |
| ISSN: | 1439-0973 |
| Popis: | The aim of this cross-sectional study was to evaluate the prevalence and risk factors of medium-grade proteinuria (100–500 mg/g creatinine) among HIV-positive adults. Spot urine samples of HIV-positive adults without known renal disease were analyzed quantitatively between January 2009 and February 2011. Demographic and medical data were collected. Multivariate regression models for different patterns of proteinuria were constructed. Among 411 patients, 18 (4.4 %) presented albuminuria >300 mg/g creatinine and/or proteinuria >500 mg/g creatinine and were excluded from further analyses. Among the study population of 393 patients, 181 (46.1 %) had no significant proteinuria or albuminuria ( |
| Databáze: | OpenAIRE |
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