Calcium signalling in platelets and other nonexcitable cells
| Autor: | Paul Sargeant, Stewart O. Sage |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Pharmacology
Blood Platelets biology Cell biology chemistry.chemical_compound Signalling Biochemistry BAPTA chemistry biology.protein Animals Humans Pharmacology (medical) Platelet Secretion Calcium Signal transduction Platelet-derived growth factor receptor Protein kinase C Calcium signaling Signal Transduction |
| Zdroj: | Pharmacologytherapeutics. 64(3) |
| ISSN: | 0163-7258 |
| Popis: | By virtue of their biological simplicity and widespread availability, platelets frequently have been used as a model system to study signal transduction. Such studies have revealed that changes in intracellular free calcium concentration are central to platelet functioning. The following article reviews current concepts of platelet structure and function, with particular emphasis on the mechanisms involved in platelet Ca2+ signalling. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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