Renal function is similar in solitary kidneys from patients with and without diabetes
| Autor: | Gheorghe Gluhovschi, Ligia Petrica, Romulus Timar, Bogdan Timar, Florica Gadalean, Silvia Velciov, Adriana Kaycsa, Cristina Gluhovschi |
|---|---|
| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Renal function 030209 endocrinology & metabolism 030230 surgery Kidney Kidney Function Tests lcsh:RC870-923 Gastroenterology Coronary artery disease Solitary Kidney 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Diabetes mellitus Diabetes Mellitus medicine Humans Diabetic Nephropathies Creatinine Proteinuria business.industry Solitary kidney (SK) Middle Aged medicine.disease lcsh:Diseases of the genitourinary system. Urology Transplantation Blood pressure Endocrinology chemistry Nephrology Uric acid Female medicine.symptom business Diabetes mellitus (DM) |
| Zdroj: | Nefrología, Vol 37, Iss 2, Pp 195-198 (2017) Nefrología (English Edition), Vol 37, Iss 2, Pp 195-198 (2017) Nefrología (Madrid) v.37 n.2 2017 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname |
| ISSN: | 0211-6995 |
| Popis: | Objectives: Due to the shortage of living kidney donors and the current diabetes mellitus (DM) pandemic, studying the association of solitary kidney (SK) with DM is of paramount importance. Our aim was to assess the significance of the association between SK and DM. Materials and methods: Eighty-four patients with SK and DM (group A), with a mean age of 62.46 ± 12.72 years, of whom 36 were males and 48 were females, were enrolled in the study. The control group (group B) comprised 84 SK patients without DM of similar age and duration of existence of a SK. Mean age: 61.58 ± 8.22 years, 23 males and 61 females. Serum creatinine, GFR (CKD-EPI), glycaemia, cholesterol, triglycerides, uric acid, proteinuria/24 h, systolic blood pressure (SBP), diastolic blood pressure (DBP) and BMI were assessed. Results: The group of patients with SK and DM (group A) had a higher BMI (p = 0.0007), higher metabolic abnormalities (higher glycaemia [p < 0.001], triglycerides [p = 0.0004], uric acid [p = 0.019] and proteinuria/24 h [p = 0.006]). The study group also had a higher prevalence of hypertension (p = 0.003) and coronary artery disease (p = 0.031). Conclusions: We found a higher value of proteinuria in the study group, significant metabolic abnormalities, as well as a higher prevalence of hypertension and coronary artery disease. However, no differences with respect to GFR were found, which could have significant implications for transplantation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|