Optical coherence tomography as a method for quantitative skin evaluation in systemic sclerosis
| Autor: | Natalia S. M. Pires, Tereza Januária Costa Dias, Marcello Magri Amaral, Angela Luzia Branco Pinto Duarte, Anderson S. L. Gomes, Luciana S. A. de Melo, Andréa Tavares Dantas, Luana Osório Fernandes |
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| Rok vydání: | 2016 |
| Předmět: |
Skin score
Adult Male medicine.medical_specialty Immunology Severity of Illness Index General Biochemistry Genetics and Molecular Biology 030207 dermatology & venereal diseases 03 medical and health sciences Young Adult 0302 clinical medicine Rheumatology Optical coherence tomography Internal medicine Healthy control Severity of illness medicine Immunology and Allergy Humans In patient skin and connective tissue diseases Aged Skin 030203 arthritis & rheumatology Scleroderma Systemic integumentary system medicine.diagnostic_test business.industry Mean age Middle Aged medicine.disease Surgery Female Radiology business Rheumatism Tomography Optical Coherence |
| Zdroj: | Annals of the rheumatic diseases. 77(3) |
| ISSN: | 1468-2060 |
| Popis: | Improved, non-invasive techniques for the diagnosis, classification and monitoring of patients with systemic sclerosis (SSc) are needed. One potential technique for quantifying the extent of cutaneous sclerosis in these patients is optical coherence tomography (OCT).1 ,2 Recently, Abignano et al 3 suggested the use of OCT as a feasible and reliable technique to evaluate skin fibrosis in SSc. Based on that initial work, the aim of this study was to evaluate OCT images and compare the findings with the modified Rodnan skin score (mRSS) in patients with SSc. Thirty-three Brazilian patients with SSc (28 women; mean age 46.1 years; range 19–71 years) were recruited and fulfilled criteria for SSc proposed by American College of Rheumatology (ACR), 19804 or ACR/European League Against Rheumatism, 2013.5 Patients were classified into limited SSc (n=18) and diffuse SSc (n=15) groups. The mean disease duration was 9.7 years (median 8 years, range 2–26 months). Thirty-five healthy control (HC) (28 women, … |
| Databáze: | OpenAIRE |
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